Interactions des alcynes avec les complexes carbéniques du tungstène portant une double liaison carbone— carbone: Accès aux dérivés bicyclo[4,1,0]. Download Citation on ResearchGate | Réaction des halogenures de titane(IV) avec les alcynes: Formation d’halogénoalcènes | The behaviour of some mono-. Download Citation on ResearchGate | Action du chlorure de fer(III) sur les alcynes: Reduction du fer(III) en fer(II) et formation d’un chloro-alcene | The behaviour.
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In addition, the results of the theoretical investigation of Chapter 2 are exploited to show how changes in the phosphorus substituents can be used to fine tune regioselectivity of alkyne cycloadditions without modifying the substituents on the final product.
X-ray crystallographic studies demonstrate the significant role of the PR3 unit on the ground state structure of these dipoles and their reactivity. Different phosphites and phosphonites are alcynfs for their ability to mediate intramolecular cycloaddition with alkenes, and optimum results are obtained with 2-catechyl PPh. Importantly, these 1,3-dipoles display divergent regioselectivity, which can be exploited to synthesize a variety of pyrroles with high selectivity through the use of the appropriate reactant.
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Molecular characterization of genes of Pseudomonas sp. Top of the page – Article Outline. In Chapter 5, a new way to control the enantioselectivity in 1,3-dipolar cycloaddition reactions is described. EP Kind code of ref document: Previous Article Gecom-Concoord As such, this provides a straightforward approach to control chirality in 1,3-dipolar cycloaddition reactions.
Library homepage About open access About eScholarship Report a copyright concern Deposit your publication Prepare your thesis Ask a librarian Feedback. Simple alkynes generate dienes via double diazoalkane carbene addition to the triple bond. All items in eScholarship McGill are protected by copyright with all rights reserved unless otherwise indicated. Comparison of three enoate reductases and their potential use for biotransformations. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters.
If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. Propargylic carboxylates lead to conjugated dienes by coupling of the diazoalkane carbene with the alkyne terminal carbon and 1,2-shift of the carboxylate.
CHIM 263 – Chimie organique II
Catalytic addition of diazoalkane carbene to propargylic compounds: Direct route to alkenyl alkylidene bicyclohexane derivatives. Catalytic addition of diazoalkane carbene to enynes: Access to the text HTML.
You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. While each of the dipoles are established to participate in 1,3-dipolar cycloaddition reactions, until now, no general rules regarding the factors that control regioselectivity have been described. Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi.
Contact Help Who are we? Record 1 of 1. Methods of refining and producing dibasic esters and acids from natural oil feedstocks. US USA1 en Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp. Outline Masquer le plan. A unique role in the addition of diazoalkane carbene to alkynes. Catalysis, Ruthenium, Diazo compounds, Carbene, Alkynes. Similarly, the rational on regioselectivity also allows the prediction of regioselectivity for a wide scope of alkynes.
Enantioselective reduction of carbonyl compounds by whole-cell biotransformation, combining a formate dehydrogenase and a R -specific alcohol dehydrogenase. Personal information regarding our website’s visitors, including their identity, is confidential.
The utility of this reaction has been extended to other products, including in situ reduction of the 2-pyrroline to pyrolidines, or oxidation to form pyrroles. Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase.
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Cloning and nucleotide sequence of fosfomycin biosynthetic genes of Streptomyces wedmorensis. Conjointement avec le Pr. The University’s open access institutional repository: Houk et le Dr. These 1,3-dipoles have been previously demonstrated to be accessible in a one-pot reaction of imines, acid chlorides and organophosphorus reagents, and participate in 1,3-dipolar cycloaddition reactions. In conjunction with Prof.
Enynes alfynes terminal triple bond lead to alkenyl bicyclo[x. You can move this window by clicking on the headline. In addition, the reaction proceeds with high diastereo- and regioselectivity.
Aryne — Wikipédia
The objective of the research described in this thesis is to both understand the reactivity of these dipoles, and alcynees their cycloaddition with alkynes and alkenes to synthesize pyrroles and 2-pyrrolines with high regio- diastereo- and enantioselectivity.
Kind code of ref document: Library homepage About open access About eScholarship Report a copyright concern. Applications of new phosphorus-based 1,3-dipolar cycloaddition reagents in nitrogen heterocycle synthesis.